SwissADME
A free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules.
Overview
SwissADME is a web-based tool developed by the Swiss Institute of Bioinformatics. It allows users to compute physicochemical descriptors and predict ADME parameters, pharmacokinetic properties, drug-like nature, and medicinal chemistry friendliness of small molecules. It is widely used in the academic community for its ease of use and the valuable information it provides for early-stage drug discovery.
✨ Key Features
- Physicochemical property prediction (logP, solubility, etc.)
- Pharmacokinetic property prediction (GI absorption, BBB permeation)
- Drug-likeness evaluation (Lipinski's rule of five, etc.)
- Medicinal chemistry friendliness assessment (PAINS alerts)
- Bioavailability score
- Free and easy to use
🎯 Key Differentiators
- User-friendly and intuitive interface
- Focus on drug-likeness and medicinal chemistry friendliness
- Boiled-Egg plot for intuitive visualization of BBB permeation and GI absorption
Unique Value: Provides a fast, free, and intuitive way for researchers to assess the drug-likeness and key ADME properties of their compounds.
🎯 Use Cases (4)
✅ Best For
- Extensively used and cited in the scientific literature.
💡 Check With Vendor
Verify these considerations match your specific requirements:
- Not intended for regulatory submissions.
- Limited number of endpoints compared to commercial software.
🏆 Alternatives
Stands out for its user-friendly interface and clear, graphical outputs that are easy to interpret.
💻 Platforms
💰 Pricing
Free tier: No explicit limits mentioned.
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