Lhasa Limited Derek Nexus
Expert knowledge-based toxicity prediction.
Overview
Derek Nexus is a knowledge-based expert system for the prediction of toxicity. It uses a proprietary knowledge base of structure-toxicity relationships to predict the likelihood of a chemical causing a range of toxicological endpoints. It is widely used for regulatory submissions and for screening compounds for potential toxicity.
✨ Key Features
- Prediction of over 40 toxicity endpoints (mutagenicity, carcinogenicity, skin sensitization, etc.)
- Knowledge-based system with clear, transparent reasoning
- Provides alerts for structural features associated with toxicity
- Used for ICH M7 guideline compliance
- Negative prediction validation
🎯 Key Differentiators
- Transparent, knowledge-based reasoning for predictions
- Strong focus on regulatory acceptance (ICH M7)
- Developed by a non-profit, collaborative organization
- Integration with other Lhasa tools for a more complete safety assessment
Unique Value: Provides transparent, scientifically robust, and regulatory-accepted toxicity predictions to ensure the safety of pharmaceuticals and chemicals.
🎯 Use Cases (4)
✅ Best For
- A leading tool for regulatory toxicity prediction, accepted by regulatory authorities worldwide.
💡 Check With Vendor
Verify these considerations match your specific requirements:
- Does not predict ADME or pharmacokinetic properties.
🏆 Alternatives
Offers a more transparent and rule-based approach to toxicity prediction compared to 'black box' machine learning models.
💻 Platforms
✅ Offline Mode Available
🔌 Integrations
🛟 Support Options
- ✓ Email Support
- ✓ Phone Support
- ✓ Dedicated Support (Standard tier)
🔒 Compliance & Security
💰 Pricing
✓ 14-day free trial
Free tier: NA
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